Lung cancer represents one of the most typical and deadliest cancers on the planet. Chimeric antigen receptor-T cell (CAR-T) therapy which might acknowledge antigens in a significant histocompatibility advanced (MHC)-independent method offers a brand new method for tumor remedy. However, lung cancer, as a stable tumor, faces a number of formidable obstacles to adoptive cell switch, which incorporates inhibition of T-cell localization and suppression of T-cell operate.
Therefore, lung cancer fails to reply considerably to infusions of CAR-T cells in most trials till now. PubMed was researched utilizing the phrases “CAR-T” and “lung cancer” solely in English from 2000 by June 2020. We additionally included outcomes offered in worldwide conferences, such because the American Society of Clinical Oncology (ASCO) and the European Society for Medical Oncology (ESMO).
Besides, we discovered new progress in CAR-T therapy for stable tumors as a complement. To improve the efficacy and conquer the restrictions, we collected some functions in lung cancer. In latest years, there have been some enhancements in choosing the right goal and lowering toxicity. CAR-T know-how offers a wonderful manner for tumor remedy, which doesn’t depend upon MHC molecules and offers a brand new technique for the utilization of tumor targets.
Targeting totally different antigens and overcoming the stable barrier, there are some enhancements in responding considerably and lowering toxicity. CAR-T know-how will play a decisive position within the remedy of lung cancer. Determining Schistosoma mansoni an infection fee and depth is difficult because of the low sensitivity of the Kato-Katz (KK) take a look at that underestimates the true illness prevalence.
Circulating cathodic antigen (CCA) excreted in urine is continually produced by grownup worms and has been used as the idea of a easy, non-invasive level of care take a look at (POC-CCA) for Schistosoma mansoni infections. Although the abundance of CCA in urine is proportional to worm burden, the POC-CCA take a look at is marketed as a qualitative take a look at, making it tough to research the wide selection of an infection intensities.
This research was designed to match the prevalence and depth of S. mansoni by KK and POC-CCA and quantify, on recent and frozen (<-20°C) urine samples, CCA utilizing the visible scores and the ESEquant LR3 reader.
Considerations for Assessment and Deployment of Rapid Antigen Tests for Diagnosis of Coronavirus Disease 2019
Diagnostic testing is a crucial instrument to mitigate the extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, however molecular testing capability stays restricted. Rapid diagnostic checks (RDTs) that detect SARS-CoV-2 protein antigens (Ag) provide the potential to considerably increase testing capability and to permit frequent, large-scale, inhabitants screening. Testing is straightforward, fast (outcomes typically accessible inside 15 minutes), and relevant for analysis at level of care.
However, implementation of Ag RDTs requires an in depth understanding of take a look at efficiency and operational traits in every testing state of affairs and inhabitants being evaluated. Successful implementation of Ag RDTs on a big scale ought to mix testing with technical oversight and with scientific and public well being infrastructure, and would require manufacturing at ranges a lot greater than presently potential.
In this commentary, we offer detailed issues for Ag RDT evaluation and use circumstances to encourage and allow broader manufacturing and deployment. The S. mansoni an infection charges inferred from POC-CCA and KK have been 40.7% and 9.4% respectively. Good correlations have been noticed between an infection intensities recorded by; i) the reader and visible scoring system on recent (Rho = 0.89) and frozen samples (Rho = 0.97), ii) the reader on recent urine samples and KK (epg) (Rho = 0.44).
Nevertheless, 238 POC-CCA optimistic kids have been unfavourable for KK, and sixteen of them had excessive ranges of CCA. The correlation between outcomes from the reader on recent and frozen samples was good (Rho = 0.85). On frozen samples, CCA was not detected in 55 samples that have been optimistic in recent urine samples.
A Biomimetic Aggregation-Induced Emission Photosensitizer with Antigen-Presenting and Hitchhiking Function for Lipid Droplet Targeted Photodynamic Immunotherapy
Photodynamic therapy (PDT) is a promising various method for efficient cancer remedy that’s related to an antitumor immune response. However, immunosuppression of the tumor microenvironment limits the immune response induced by PDT. Stimulation and proliferation of T cells is a crucial step for producing immune responses and is dependent upon the environment friendly presentation of tumor antigens and co-stimulatory molecules by antigen-presenting cells (APCs).
Here, biomimetic aggregation-induced emission (AIE) photosensitizers with antigen-presenting and hitchhiking skills (DC@AIEdots) are developed by coating dendritic cell (DC) membranes on the nanoaggregates of the AIEgens. Notably, the internal AIE molecules can selectively accumulate in lipid droplets of tumor cells, and the outer cell membrane can facilitate the hitchhiking of DC@AIEdots onto the endogenous T cells and improve the tumor supply effectivity by about 1.6 occasions.
Furthermore, DC@AIEdots can stimulate the in vivo proliferation and activation of T cells and set off the immune system. The potential functions of therapeutic brokers concentrating on lipid droplets for immunotherapy are indicated and a brand new hitchhiking method for drug supply is offered. Lastly, the research presents a photoactive and synthetic antigen-presenting platform for efficient T cell stimulation and cancer photodynamic immunotherapy.
Unusual aggregation property of recombinantly expressed cancer-testis antigens in mammalian cells
Transient expression of human intracellular proteins in human embryonic kidney (HEK) 293 cells is a dependable system for acquiring soluble proteins with biologically lively conformations. Contrary to standard ideas, we discovered that recombinantly expressed intracellular cancer-testis antigens (CTAs) confirmed frequent aggregation in HEK293 cells.
Although experimental subcellular localization of recombinant CTAs displayed correct cytosolic or nuclear localization, some proteins confirmed aggregated particles within the cell. This aggregative property was not noticed in recombinant housekeeping proteins.
baculoCOMPLETE protein expression kit + baculoQUANT all-in-one |
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| 400101 | Oxford Expression Technologies | 5 + 100 reactions | 1009.89 EUR |
Human RHCE Protein Lysate |
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| MBS8418565-002mg | MyBiosource | 0.02mg | 365 EUR |
Human RHCE Protein Lysate |
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| MBS8418565-5x002mg | MyBiosource | 5x0.02mg | 1410 EUR |
Human RHCE Protein Lysate 20ug |
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| IHURHCEPLLY20UG | Innovative research | each | 213 EUR |
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Description: Human RHCE Protein Lysate 20ug |
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EP Reagent Biuret Reagent - 100ML |
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| 1011601 | Scientific Laboratory Supplies | 1L | 59.4 EUR |
PEROXIDE BLOCKING REAGENT Reagent |
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| GWB-Q00308 | GenWay Biotech | 50 ml | Ask for price |
EP Reagent Iodoplatinate Reagent - 200ML |
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| 1046300 | Scientific Laboratory Supplies | 200ML | 502.2 EUR |
EP Reagent Molybdovanadic Reagent - 100ML |
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| 1056700 | Scientific Laboratory Supplies | 100ML | 59.4 EUR |
OCOA02528-20UG - RHCE Protein Lysate |
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| OCOA02528-20UG | Aviva Systems Biology | 20ug | 169 EUR |
OCOA06391-20UG - RHCE Protein Lysate |
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| OCOA06391-20UG | Aviva Systems Biology | 20ug | 169 EUR |
OCOA06392-20UG - RHCE Protein Lysate |
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| OCOA06392-20UG | Aviva Systems Biology | 20ug | 169 EUR |
EP Reagent Methoxyphenylacetic Reagent - 100ML |
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| 1053601 | Scientific Laboratory Supplies | 100ML | 490.05 EUR |
Protein expression |
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| CRO-4-Ind | Jotbody | each | Ask for price |
EP Reagent Phosphomolybdotungstic Reagent - 100ML |
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| 1065000 | Scientific Laboratory Supplies | 100ML | 226.8 EUR |
RFP expression Adenovirus, in vivo ready |
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| AVP001-PBS | GenTarget | 1x1011 IFU/ml x 50ul | 455 EUR |
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Description: pre-made RFP expression adenovirus, provided in PBS solution. |
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CFP expression Adenovirus, in vivo ready |
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| AVP002-PBS | GenTarget | 1x1011 IFU/ml x 50ul | 455 EUR |
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Description: pre-made CFP expression adenovirus, provided in PBS solution. |
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GFP expression Adenovirus, in vivo ready |
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| AVP011-PBS | GenTarget | 1x1011 IFU/ml x 50ul | 455 EUR |
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Description: pre-made GFP expression adenovirus, provided in PBS solution. |
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YFP expression Adenovirus, in vivo ready |
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| AVP012-PBS | GenTarget | 1x1011 IFU/ml x 50ul | 455 EUR |
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Description: pre-made YFP expression adenovirus, provided in PBS solution. |
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BFP expression Adenovirus, in vivo ready |
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| AVP017-PBS | GenTarget | 1x1011 IFU/ml x 50ul | 455 EUR |
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Description: pre-made BFP expression adenovirus, provided in PBS solution. |
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AVIDIN/BIOTIN BLOCKING REAGENT Reagent |
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| GWB-Q00289 | GenWay Biotech | 30 ml | Ask for price |
Gordon-McLeod Reagent (Oxidase reagent) |
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| R026-100ML | EWC Diagnostics | 1 unit | 7.76 EUR |
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Description: Gordon-McLeod Reagent (Oxidase reagent) |
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Oxidase Reagent (Gordon-Macleod Reagent) |
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| 76207 | Sisco Laboratories | 100 ml | 3.38 EUR |
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Description: Part B |
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YLEX Expression Kit |
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| FYY201-1KT | Yeastern Biotech | 1 kit | Ask for price |
RHCG (NM_016321) Human Over-expression Lysate |
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| E45H10030-2 | EnoGene | each | 395 EUR |
RHCG (NM_016321) Human Over-expression Lysate |
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| LS051458 | BosterBio | 100ug | 628 EUR |
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Description: Transient overexpression lysate of Rh family, C glycoprotein (RHCG) |
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EP Reagent Sulfomolybdic Reagent R3 - 1L |
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| 1086500 | Scientific Laboratory Supplies | 1L | 398.25 EUR |
TRIpure Reagent (same as Trizol Reagent) |
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| MBS356001-INQUIRE | MyBiosource | INQUIRE | Ask for price |
h OCT4 expression Adenovirus, in vivo ready |
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| AVP013-PBS | GenTarget | 1x1011 IFU/ml x 50ul | 455 EUR |
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Description: pre-made adenovirus express human stem cell factor, OCT4, provided in PBS solution for in vivo application. |
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h SOX2 expression Adenovirus, in vivo ready |
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| AVP014-PBS | GenTarget | 1x1011 IFU/ml x 50ul | 455 EUR |
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Description: pre-made adenovirus express human stem cell factor, SOX2, provided in PBS solution for in vivo application. |
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293 Expression MAX-1 |
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| EXP-711-11 | ACROBIOSYSTEMS | 1ml | 218 EUR |
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Description: 293 Expression MAX-1 is expressed from - -. |
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R3HCC1 (NM_001136108) Human Over-expression Lysate |
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| E45H01883-2 | EnoGene | each | 395 EUR |
R3HCC1 (NM_001136108) Human Over-expression Lysate |
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| LS203069 | BosterBio | 100ug | 628 EUR |
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Description: Antigen standard for R3H domain and coiled-coil containing 1 (R3HCC1) (transient overexpression lysate) |
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h LIN28 expression Adenovirus, in vivo ready |
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| AVP015-PBS | GenTarget | 1x1011 IFU/ml x 50ul | 455 EUR |
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Description: pre-made adenovirus express human stem cell factor, LIN28, provided in PBS solution for in vivo application. |
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Total RNA Isolation Reagent (Reagent Based) |
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| MBS402052-100mL | MyBiosource | 100mL | 235 EUR |
Total RNA Isolation Reagent (Reagent Based) |
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| MBS402052-4Reactions | MyBiosource | 4Reactions | 165 EUR |
Genomic DNA Isolation Reagent (Reagent Based) |
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| MBS402050-100mL | MyBiosource | 100mL | 255 EUR |
Genomic DNA Isolation Reagent (Reagent Based) |
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| MBS402050-4Reactions | MyBiosource | 4Reactions | 185 EUR |
CNGA2 Expression vector |
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| 60642 | BPS Bioscience | 20 µg | 900 EUR |
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Description: The CNGA2 expression vector is designed to express human cyclic nucleotide-gated cation channel 2 (CNGA2) in mammalian cells. |
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CNGA2 Expression vector |
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| GWB-PSFA61 | GenWay Biotech | 20ug | Ask for price |
pYLEX1 - Expression Vector |
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| FYY203-5MG | Yeastern Biotech | 5mg | Ask for price |
LEXSYcon2.1 Expression Kit |
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| EGE-1310ble | Jena Bioscience GmbH | 1Kit | 979.85 EUR |
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Description: for constitutive cytosolic or secretory protein expression |
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LEXSYcon2.1 Expression Kit |
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| EGE-1310bsd | Jena Bioscience GmbH | 1Kit | 979.85 EUR |
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Description: for constitutive cytosolic or secretory protein expression |
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LEXSYcon2.1 Expression Kit |
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| EGE-1310hyg | Jena Bioscience GmbH | 1Kit | 979.85 EUR |
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Description: for constitutive cytosolic or secretory protein expression |
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LEXSYcon2.1 Expression Kit |
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| EGE-1310neo | Jena Bioscience GmbH | 1Kit | 979.85 EUR |
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Description: for constitutive cytosolic or secretory protein expression |
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LEXSYcon2.1 Expression Kit |
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| EGE-1310pac | Jena Bioscience GmbH | 1Kit | 979.85 EUR |
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Description: for constitutive cytosolic or secretory protein expression |
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LEXSYcon2.1 Expression Kit |
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| EGE-1310sat | Jena Bioscience GmbH | 1Kit | 979.85 EUR |
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Description: for constitutive cytosolic or secretory protein expression |
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Blunt E1 Expression Kit |
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| abx098098-100l | Abbexa | 100 µl | 712.5 EUR |
Blunt E1 Expression Kit |
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| abx098098-10rxns | Abbexa | 10 rxns | 560.4 EUR |
Blunt E1 Expression Kit |
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| abx098098-1ml | Abbexa | 1 ml | Ask for price |
Blunt E1 Expression Kit |
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| abx098098-200l | Abbexa | 200 µl | Ask for price |
Blunt E2 Expression Kit |
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| abx098873-100l | Abbexa | 100 µl | 712.5 EUR |
Blunt E2 Expression Kit |
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| abx098873-10rxns | Abbexa | 10 rxns | 560.4 EUR |
Blunt E2 Expression Kit |
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| abx098873-1ml | Abbexa | 1 ml | Ask for price |
Blunt E2 Expression Kit |
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| abx098873-200l | Abbexa | 200 µl | Ask for price |
RFP expression Adenovirus |
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| AVP001 | GenTarget | 1x109 IFU/ml x 200ul | 206.5 EUR |
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Description: pre-made RFP expression adenovirus, provided in DMEM medium. |
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CFP expression Adenovirus |
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| AVP002 | GenTarget | 1x109 IFU/ml x 200ul | 206.5 EUR |
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Description: pre-made CFP expression adenovirus, provided in DMEM medium. |
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GFP expression Adenovirus |
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| AVP011 | GenTarget | 1x109 IFU/ml x 200ul | 206.5 EUR |
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Description: pre-made GFP expression adenovirus, provided in DMEM medium. |
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YFP expression Adenovirus |
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| AVP012 | GenTarget | 1x109 IFU/ml x 200ul | 206.5 EUR |
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Description: pre-made YFP expression adenovirus, provided in DMEM medium. |
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BFP expression Adenovirus |
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| AVP017 | GenTarget | 1x109 IFU/ml x 200ul | 206.5 EUR |
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Description: pre-made BFP expression adenovirus, provided in DMEM medium. |
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LEXSinduce3 Expression Kit |
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| EGE-1410ble | Jena Bioscience GmbH | 1Kit | 2296.43 EUR |
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Description: for inducible cytosolic or secretory protein expression |
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LEXSinduce3 Expression Kit |
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| EGE-1410blecherry | Jena Bioscience GmbH | 1Kit | 2296.43 EUR |
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Description: for inducible cytosolic or secretory protein expression |
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LEXSinduce3 Expression Kit |
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| EGE-1410neo | Jena Bioscience GmbH | 1Kit | 2296.43 EUR |
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Description: for inducible cytosolic or secretory protein expression |
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LEXSinduce4 Expression Kit |
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| EGE-1420blecherry | Jena Bioscience GmbH | 1Kit | 2296.43 EUR |
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Description: for inducible cytosolic or secretory protein expression |
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Rac1 Expression Vector Set |
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| STA-454 | Cell Biolabs | 1 kit | 1765.2 EUR |
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Description: Rac1 Expression Vector Set contains 3 vectors: Rac wild type, T17N dominant negative mutant, and G12V constitutively active mutant. |
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RhoA Expression Vector Set |
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| STA-456 | Cell Biolabs | 1 kit | 1765.2 EUR |
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Description: RhoA Expression Vector Set contains 3 vectors: RhoA wild type, T19N dominant negative mutant, and G14V constitutively active mutant. |
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Plant Total RNA Isolation Reagent (Reagent Based) |
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| MBS402053-100mL | MyBiosource | 100mL | 245 EUR |
Plant Total RNA Isolation Reagent (Reagent Based) |
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| MBS402053-4Reactions | MyBiosource | 4Reactions | 165 EUR |
OPN expression inhibitor 1 |
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| HY-146064 | MedChemExpress | 10 mg | 2272.76 EUR |
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Description: OPN expression inhibitor 1 (Compound 11) is an osteopontin (OPN) expression inhibitor. OPN expression inhibitor 1 can be used for breast cancer research[1]. |
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Cdc42 Expression Vector Set |
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| STA-455 | Cell Biolabs | 1 kit | 1765.2 EUR |
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Description: Cdc42 Expression Vector Set contains 3 vectors: Cdc42 wild type, T17N dominant negative mutant, and Q61L constitutively active mutant. |
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OPN expression inhibitor 1 |
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| T62820-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: OPN expression inhibitor 1 |
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OPN expression inhibitor 1 |
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| T62820-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: OPN expression inhibitor 1 |
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OPN expression inhibitor 1 |
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| T62820-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: OPN expression inhibitor 1 |
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OPN expression inhibitor 1 |
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| T62820-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: OPN expression inhibitor 1 |
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OPN expression inhibitor 1 |
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| T62820-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: OPN expression inhibitor 1 |
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Plant Genomic DNA Isolation Reagent (Reagent Based) |
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| MBS402051-100mL | MyBiosource | 100mL | 245 EUR |
Plant Genomic DNA Isolation Reagent (Reagent Based) |
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| MBS402051-4Reactions | MyBiosource | 4Reactions | 165 EUR |
h FAP Expression Lentivirus |
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| LVP1307 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
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Description: Over-expression lentivirus for human target: FAP, containing a RFP-Blasticidin dual selection marker. |
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h CD1 Expression Lentivirus |
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| LVP1320 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
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Description: Over-expression lentivirus for human target: CD1, containing a RFP-Blasticidin dual selection marker. |
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m FAP Expression Lentivirus |
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| LVP1326 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
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Description: Over-expression lentivirus for mouse target: FAP, containing a RFP-Blasticidin dual selection marker. |
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h VIM Expression Lentivirus |
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| LVP1357 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
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Description: Over-expression lentivirus for human target: VIM, containing a RFP-Blasticidin dual selection marker. |
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h PXN Expression Lentivirus |
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| LVP1358 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
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Description: Over-expression lentivirus for human target: PXN, containing a RFP-Blasticidin dual selection marker. |
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m CD8 Expression Lentivirus |
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| LVP1363 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
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Description: Over-expression lentivirus for mouse target: CD8, containing a RFP-Blasticidin dual selection marker. |
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h TPO Expression Lentivirus |
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| LVP1371 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
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Description: Over-expression lentivirus for human target: TPO, containing a RFP-Blasticidin dual selection marker. |
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h WAS Expression Lentivirus |
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| LVP1429 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
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Description: Over-expression lentivirus for human target: WAS, containing a RFP-Blasticidin dual selection marker. |
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m PGR Expression Lentivirus |
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| LVP1455 | GenTarget | 1x10^7 IFU/ml x 200ul | 346.5 EUR |
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Description: Pre-made over-expression lentivirus for mouse target: PGR containing a RFP-Blasticidin dual selection marker. |
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h MAG Expression Lentivirus |
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| LVP1485 | GenTarget | 1x10^7 IFU/ml x 200ul | 346.5 EUR |
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Description: Pre-made over-expression lentivirus for human target: MAG, containing a RFP-Blasticidin dual selection marker. |
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h FST Expression Lentivirus |
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| LVP1518 | GenTarget | 1x10^8 IFU/ml x 200ul | 455 EUR |
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Description: Pre-made lentivirus express human FST gene, containing a RFP-Blasticidin dual selection marker. |
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h IL2 Expression Lentivirus |
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| LVP293 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
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Description: Lentivirus express a human IL2 gene with a Blasticidin-RFP fusion marker (Dual selection). |
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h ADA Expression Lentivirus |
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| LVP923 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: ADA, containing a RFP-Blasticidin dual selection marker. |
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h PBK Expression Lentivirus |
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| LVP095 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made Lentivirus express human PBK gene, carrying a RFP-Blasticidin fusion marker (Dual selection). |
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h IL6 Expression Lentivirus |
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| LVP1144 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
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Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker. |
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h CD4 Expression Lentivirus |
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| LVP1152 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
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Description: Pre-made over-expression lentivirus for human target: CD4, containing a RFP-Blasticidin dual selection marker. |
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h IL4 Expression Lentivirus |
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| LVP1161 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: IL4, containing a RFP-Blasticidin dual selection marker. |
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h IL7 Expression Lentivirus |
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| LVP1162 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
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Description: Pre-made over-expression lentivirus for human target: IL7, containing a RFP-Blasticidin dual selection marker. |
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pAAV-MCS Expression Vector |
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| MBS169528-001mg | MyBiosource | 0.01mg | 695 EUR |
pAAV-MCS Expression Vector |
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| MBS169528-5x001mg | MyBiosource | 5x0.01mg | 2955 EUR |
pAAV-MCS Expression Vector |
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| VPK-410 | Cell Biolabs | 10 µg | 444 EUR |
ExoPure? Reagent (Overall Exosome Isolation, urine) |
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| M1003-25 | Biovision | each | 992.4 EUR |
ExoPure? Reagent (Overall Exosome Isolation, urine) |
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| M1003-50 | Biovision | each | 1083.6 EUR |
FlashBAC - Baculovirus Expression System (96 reactions) |
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| GWB-6C34E3 | GenWay Biotech | Kit | Ask for price |
FlashBAC - Baculovirus Expression System (5 reactions) |
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| GWB-7676BB | GenWay Biotech | Kit | Ask for price |
FlashBAC - Baculovirus Expression System(24 reactions) |
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| GWB-EB1FF8 | GenWay Biotech | Kit | Ask for price |
h OCT4 expression Adenovirus |
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| AVP013 | GenTarget | 1x109 IFU/ml x 200ul | 206.5 EUR |
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Description: pre-made adenovirus express human stem cell factor, OCT4, provided in DMEM medium. |
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h SOX2 expression Adenovirus |
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| AVP014 | GenTarget | 1x109 IFU/ml x 50ul | 206.5 EUR |
|
Description: pre-made adenovirus express human stem cell factor, SOX2, provided in DMEM medium. |
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h CBX7 Expression Lentivirus |
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| LVP1308 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: CBX7, containing a RFP-Blasticidin dual selection marker. |
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h ACE2 Expression Lentivirus |
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| LVP1310 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
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Description: Over-expression lentivirus for human target: ACE2, containing a RFP-Blasticidin dual selection marker. |
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h Rab7 Expression Lentivirus |
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| LVP1315 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
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Description: Over-expression lentivirus for human target: Rab7, containing a RFP-Blasticidin dual selection marker. |
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h Rab5 Expression Lentivirus |
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| LVP1316 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: Rab5, containing a RFP-Blasticidin dual selection marker. |
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m ASPA Expression Lentivirus |
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| LVP1317 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for mouse target: ASPA, containing a RFP-Blasticidin dual selection marker. |
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h CD44 Expression Lentivirus |
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| LVP1318 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: CD44, containing a RFP-Blasticidin dual selection marker. |
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h MFN2 Expression Lentivirus |
|||
| LVP1327 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: MFN2, containing a RFP-Blasticidin dual selection marker. |
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h ANO1 Expression Lentivirus |
|||
| LVP1344 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: ANO1 containing a RFP-Blasticidin dual selection marker. |
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h FGL2 Expression Lentivirus |
|||
| LVP1346 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: FGL2, containing a RFP-Blasticidin dual selection marker. |
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h CCR2 Expression Lentivirus |
|||
| LVP1354 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: CCR2, containing a RFP-Blasticidin dual selection marker. |
|||
h NEFL Expression Lentivirus |
|||
| LVP1360 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: NEFL, containing a RFP-Blasticidin dual selection marker. |
|||
h NOS2 Expression Lentivirus |
|||
| LVP1367 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: NOS2, containing a RFP-Blasticidin dual selection marker. |
|||
h BMI1 Expression Lentivirus |
|||
| LVP1372 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: BMI1, containing a RFP-Blasticidin dual selection marker. |
|||
h PSCA Expression Lentivirus |
|||
| LVP1374 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: PSCA, containing a RFP-Blasticidin dual selection marker. |
|||
h POLQ Expression Lentivirus |
|||
| LVP1421 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: POLQ containing a RFP-Blasticidin dual selection marker. |
|||
h ARSA Expression Lentivirus |
|||
| LVP1425 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: ARSA, containing a RFP-Blasticidin dual selection marker. |
|||
h IDUA Expression Lentivirus |
|||
| LVP1426 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: IDUA, containing a RFP-Blasticidin dual selection marker. |
|||
h SGSH Expression Lentivirus |
|||
| LVP1427 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: SGSH, containing a RFP-Blasticidin dual selection marker. |
|||
h CYBB Expression Lentivirus |
|||
| LVP1430 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: CYBB, containing a RFP-Blasticidin dual selection marker. |
|||
h CAV1 Expression Lentivirus |
|||
| LVP1431 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: CAV1, containing a RFP-Blasticidin dual selection marker. |
|||
m INS2 Expression Lentivirus |
|||
| LVP1456 | GenTarget | 1x10^7 IFU/ml x 200ul | 346.5 EUR |
|
Description: Pre-made over-expression lentivirus for mouse target: INS2 containing a RFP-Blasticidin dual selection marker. |
|||
h ROR1 Expression Lentivirus |
|||
| LVP1458 | GenTarget | 1x10^7 IFU/ml x 200ul | 346.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: ROR1, containing a RFP-Blasticidin dual selection marker. |
|||
h DGKA Expression Lentivirus |
|||
| LVP1468 | GenTarget | 1x10^7 IFU/ml x 200ul | 346.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: DGKA, containing a RFP-Blasticidin dual selection marker. |
|||
h REST_HA Expression Lentivirus |
|||
| LVP1475 | GenTarget | 1x10^7 IFU/ml x 200ul | 346.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: REST, containing a RFP-Blasticidin dual selection marker. |
|||
h UBR7 Expression Lentivirus |
|||
| LVP1483 | GenTarget | 1x10^7 IFU/ml x 200ul | 346.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: UBR7, containing a RFP-Blasticidin dual selection marker. |
|||
h MMP1 Expression Lentivirus |
|||
| LVP1516 | GenTarget | 1x10^8 IFU/ml x 200ul | 455 EUR |
|
Description: Pre-made lentivirus express human MMP1 gene, containing a RFP-Blasticidin dual selection marker. |
|||
h BDNF Expression Lentivirus |
|||
| LVP1520 | GenTarget | 1x10^8 IFU/ml x 200ul | 455 EUR |
|
Description: Pre-made lentivirus express human BDNF gene, containing a RFP-Blasticidin dual selection marker. |
|||
m CCL5 Expression Lentivirus |
|||
| LVP1619 | GenTarget | 1x10^8 IFU/ml x 200ul | 455 EUR |
|
Description: Pre-made lentivirus express mouse CCL5 gene, containing a RFP-Blasticidin dual selection marker. |
|||
h TET2 Expression Lentivirus |
|||
| LVP875 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made lentivirus express human target: TET2 (tet methylcytosine dioxygenase 2). It contains a RFP-Blasticidin dual selection marker. |
|||
h TET3 Expression Lentivirus |
|||
| LVP876 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for expressing human target: TET3 (tet methylcytosine dioxygenase 3), [alternative names: hCG_40738]. The sub-cloned codon sequence is identical (100% match) to CDS region in NCBI ID: NM_001287491.1 . It also contains a RFP-Blasticidin dual selection marker. |
|||
h CDR1 Expression Lentivirus |
|||
| LVP917 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: CDR1, containing a RFP-Blasticidin dual selection marker. |
|||
h CD47 Expression Lentivirus |
|||
| LVP918 | GenTarget | 1x107 IFU/ml x 200ul | 541.2 EUR |
|
Description: Pre-made over-expression lentivirus for human target: CD47, containing a RFP-Blasticidin dual selection marker. |
|||
h ESR1 Expression Lentivirus |
|||
| LVP924 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: ESR1, containing a RFP-Blasticidin dual selection marker. |
|||
r Syn1 Expression Lentivirus |
|||
| LVP925 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for rat target: Syn1, containing a RFP-Blasticidin dual selection marker. |
|||
h NME4 Expression Lentivirus |
|||
| LVP932 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: NME4, containing a RFP-Blasticidin dual selection marker. |
|||
h EGFR Expression Lentivirus |
|||
| LVP1142 | GenTarget | 1x107 IFU/ml x 200ul | 541.2 EUR |
|
Description: Pre-made over-expression lentivirus for human target: EGFR, containing a RFP-Blasticidin dual selection marker. |
|||
h CD8a Expression Lentivirus |
|||
| LVP1151 | GenTarget | 1x107 IFU/ml x 200ul | 541.2 EUR |
|
Description: Pre-made over-expression lentivirus for human target: CD8a, containing a RFP-Blasticidin dual selection marker. |
|||
h PIGF Expression Lentivirus |
|||
| LVP1154 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: PIGF, containing a RFP-Blasticidin dual selection marker. |
|||
h BRAF Expression Lentivirus |
|||
| LVP1156 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: BRAF, containing a RFP-Blasticidin dual selection marker. |
|||
h ROS1 Expression Lentivirus |
|||
| LVP1158 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: ROS1, containing a RFP-Blasticidin dual selection marker. |
|||
h CD3E Expression Lentivirus |
|||
| LVP1163 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: IL7, containing a RFP-Blasticidin dual selection marker. |
|||
h KLK3 Expression Lentivirus |
|||
| LVP1171 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: KLK3, containing a RFP-Blasticidin dual selection marker. |
|||
h NEK6 Expression Lentivirus |
|||
| LVP1182 | GenTarget | 1x107 IFU/ml x 200ul | 541.2 EUR |
|
Description: Pre-made over-expression lentivirus for human target: NEK6, containing a RFP-Blasticidin dual selection marker. |
|||
h NEK7 Expression Lentivirus |
|||
| LVP1183 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: NEK7, containing a RFP-Blasticidin dual selection marker. |
|||
h STM2 Expression Lentivirus |
|||
| LVP1210 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: STM2, containing a RFP-Blasticidin dual selection marker. |
|||
N.N.C.D.-reagent |
|||
| N632003 | Toronto Research Chemicals | 1g | 1200 EUR |
|
Description: 6035-19-4 |
|||
H-Ras Expression Vector Set |
|||
| STA-457 | Cell Biolabs | 1 kit | 1765.2 EUR |
|
Description: H-Ras Expression Vector Set contains 3 vectors: H-Ras wild type, T19N dominant negative mutant, and G12V constitutively active mutant. |
|||
h LIN28 expression Adenovirus |
|||
| AVP015 | GenTarget | 1x109 IFU/ml x 200ul | 206.5 EUR |
|
Description: pre-made adenovirus express human stem cell factor, LIN28, provided in DMEM medium. |
|||
h FADS2 Expression Lentivirus |
|||
| LVP1319 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: FADS2, containing a RFP-Blasticidin dual selection marker. |
|||
h OVOL2 Expression Lentivirus |
|||
| LVP1322 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: OVOL2, containing a RFP-Blasticidin dual selection marker. |
|||
h APOA1 Expression Lentivirus |
|||
| LVP1324 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: APOA1, containing a RFP-Blasticidin dual selection marker. |
|||
h SOX10 Expression Lentivirus |
|||
| LVP1325 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: SOX10, containing a RFP-Blasticidin dual selection marker. |
|||
h P2RY1 Expression Lentivirus |
|||
| LVP1328 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: P2RY1, containing a RFP-Blasticidin dual selection marker. |
|||
h TUSC2 Expression Lentivirus |
|||
| LVP1343 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: TUSC2, containing a RFP-Blasticidin dual selection marker. |
|||
h NLRP3 Expression Lentivirus |
|||
| LVP1350 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: NLRP3, containing a RFP-Blasticidin dual selection marker. |
|||
h CCL19 Expression Lentivirus |
|||
| LVP1353 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: CCL19, containing a RFP-Blasticidin dual selection marker. |
|||
h Sirt2 Expression Lentivirus |
|||
| LVP1373 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: Sirt2, containing a RFP-Blasticidin dual selection marker. |
|||
h EPCAM Expression Lentivirus |
|||
| LVP1375 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: EPCAM, containing a RFP-Blasticidin dual selection marker. |
|||
h PDE6B Expression Lentivirus |
|||
| LVP1423 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: PDE6B, containing a RFP-Blasticidin dual selection marker. |
|||
h ABCA4 Expression Lentivirus |
|||
| LVP1424 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: ABCA4, containing a RFP-Blasticidin dual selection marker. |
|||
h NAGLU Expression Lentivirus |
|||
| LVP1428 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: NAGLU, containing a RFP-Blasticidin dual selection marker. |
|||
h ACOD1 Expression Lentivirus |
|||
| LVP1432 | GenTarget | 1x10^7 IFU/ml x 200ul | 276.5 EUR |
|
Description: Over-expression lentivirus for human target: ACOD1, containing a RFP-Blasticidin dual selection marker. |
|||
h SIRPA Expression Lentivirus |
|||
| LVP1459 | GenTarget | 1x10^7 IFU/ml x 200ul | 346.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: SIRPA, containing a RFP-Blasticidin dual selection marker. |
|||
h RIOK1 Expression Lentivirus |
|||
| LVP1469 | GenTarget | 1x10^7 IFU/ml x 200ul | 346.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: RIOK1, containing a RFP-Blasticidin dual selection marker. |
|||
h HDAC8 Expression Lentivirus |
|||
| LVP1482 | GenTarget | 1x10^7 IFU/ml x 200ul | 346.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: HDAC8, containing a RFP-Blasticidin dual selection marker. |
|||
h CD226 Expression Lentivirus |
|||
| LVP1484 | GenTarget | 1x10^7 IFU/ml x 200ul | 346.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: CD226, containing a RFP-Blasticidin dual selection marker. |
|||
h TAOK1 Expression Lentivirus |
|||
| LVP1509 | GenTarget | 1x10^8 IFU/ml x 200ul | 455 EUR |
|
Description: Pre-made lentivirus express human TAOK1 gene, containing a RFP-Blasticidin dual selection marker. |
|||
h CD155 Expression Lentivirus |
|||
| LVP1512 | GenTarget | 1x10^8 IFU/ml x 200ul | 455 EUR |
|
Description: Pre-made lentivirus express human CD155 gene, containing a RFP-Blasticidin dual selection marker. |
|||
h GSTA1 Expression Lentivirus |
|||
| LVP1514 | GenTarget | 1x10^8 IFU/ml x 200ul | 455 EUR |
|
Description: Pre-made lentivirus express human GSTA1 gene, containing a RFP-Blasticidin dual selection marker. |
|||
h GSTA2 Expression Lentivirus |
|||
| LVP1515 | GenTarget | 1x10^8 IFU/ml x 200ul | 455 EUR |
|
Description: Pre-made lentivirus express human GSTA2 gene, containing a RFP-Blasticidin dual selection marker. |
|||
m CXCL9 Expression Lentivirus |
|||
| LVP1620 | GenTarget | 1x10^8 IFU/ml x 200ul | 455 EUR |
|
Description: Pre-made lentivirus express mouse CXCL9 gene, containing a RFP-Blasticidin dual selection marker. |
|||
h TACC3 Expression Lentivirus |
|||
| LVP594 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made optional inducible lentiviral particles for expressing human target: h TACC3 (alternative name: ERIC-1; ERIC1). The sub-cloned codon sequence is identical (100% match) to CDS region in NCBI ID: NM_006342.2. Particles also contains a RFP-Blasticidin dual selection marker. |
|||
h GPNMB Expression Lentivirus |
|||
| LVP921 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: GPNMB, containing a RFP-Blasticidin dual selection marker. |
|||
h DECR1 Expression Lentivirus |
|||
| LVP927 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: DECR1, containing a RFP-Blasticidin dual selection marker. |
|||
h DECR2 Expression Lentivirus |
|||
| LVP928 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: DECR2, containing a RFP-Blasticidin dual selection marker. |
|||
h NMRK1 Expression Lentivirus |
|||
| LVP930 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: NMRK1, containing a RFP-Blasticidin dual selection marker. |
|||
h PITX3 Expression Lentivirus |
|||
| LVP931 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: PITX3, containing a RFP-Blasticidin dual selection marker. |
|||
h ZRSR2 Expression Lentivirus |
|||
| LVP1118 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for expressing human target: ZRSR2 (zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2), [alternative names: U2AF1-RS2; U2AF1L2; U2AF1RS2; URP; ZC3H22]. The sub-cloned codon sequence is identical (100% match) to CDS region in NCBI ID: NM_005089. It also contains a RFP-Blasticidin dual selection marker. |
|||
h HDAC1 Expression Lentivirus |
|||
| LVP1143 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker. |
|||
h VEGFB Expression Lentivirus |
|||
| LVP1146 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker. |
|||
h PARP1 Expression Lentivirus |
|||
| LVP1149 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker. |
|||
h IL3RA Expression Lentivirus |
|||
| LVP1150 | GenTarget | 1x107 IFU/ml x 200ul | 541.2 EUR |
|
Description: Pre-made over-expression lentivirus for human target: IL3RA, containing a RFP-Blasticidin dual selection marker. |
|||
h PTCH1 Expression Lentivirus |
|||
| LVP1155 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: PTCH1, containing a RFP-Blasticidin dual selection marker. |
|||
h SART3 Expression Lentivirus |
|||
| LVP1159 | GenTarget | 1x107 IFU/ml x 200ul | 276.5 EUR |
|
Description: Pre-made over-expression lentivirus for human target: SART3, containing a RFP-Blasticidin dual selection marker. |
|||
No important correlation was discovered between the aggregative and biophysical properties, reminiscent of hydrophobicity, contents of intrinsically disordered areas, and expression ranges, of CTAs.