A narrative review of chimeric antigen receptor-T (CAR-T) cell therapy for lung cancer

A narrative review of chimeric antigen receptor-T (CAR-T) cell therapy for lung cancer

Posted on by Faith

Lung cancer represents one of the most typical and deadliest cancers on the planet. Chimeric antigen receptor-T cell (CAR-T) therapy which might acknowledge antigens in a significant histocompatibility advanced (MHC)-independent method offers a brand new method for tumor remedy. However, lung cancer, as a stable tumor, faces a number of formidable obstacles to adoptive cell switch, which incorporates inhibition of T-cell localization and suppression of T-cell operate.

Therefore, lung cancer fails to reply considerably to infusions of CAR-T cells in most trials till now. PubMed was researched utilizing the phrases “CAR-T” and “lung cancer” solely in English from 2000 by June 2020. We additionally included outcomes offered in worldwide conferences, such because the American Society of Clinical Oncology (ASCO) and the European Society for Medical Oncology (ESMO).

Besides, we discovered new progress in CAR-T therapy for stable tumors as a complement. To improve the efficacy and conquer the restrictions, we collected some functions in lung cancer. In latest years, there have been some enhancements in choosing the right goal and lowering toxicity. CAR-T know-how offers a wonderful manner for tumor remedy, which doesn’t depend upon MHC molecules and offers a brand new technique for the utilization of tumor targets.

Targeting totally different antigens and overcoming the stable barrier, there are some enhancements in responding considerably and lowering toxicity. CAR-T know-how will play a decisive position within the remedy of lung cancer. Determining Schistosoma mansoni an infection fee and depth is difficult because of the low sensitivity of the Kato-Katz (KK) take a look at that underestimates the true illness prevalence.

Circulating cathodic antigen (CCA) excreted in urine is continually produced by grownup worms and has been used as the idea of a easy, non-invasive level of care take a look at (POC-CCA) for Schistosoma mansoni infections. Although the abundance of CCA in urine is proportional to worm burden, the POC-CCA take a look at is marketed as a qualitative take a look at, making it tough to research the wide selection of an infection intensities.

This research was designed to match the prevalence and depth of S. mansoni by KK and POC-CCA and quantify, on recent and frozen (<-20°C) urine samples, CCA utilizing the visible scores and the ESEquant LR3 reader.

Considerations for Assessment and Deployment of Rapid Antigen Tests for Diagnosis of Coronavirus Disease 2019

Diagnostic testing is a crucial instrument to mitigate the extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, however molecular testing capability stays restricted. Rapid diagnostic checks (RDTs) that detect SARS-CoV-2 protein antigens (Ag) provide the potential to considerably increase testing capability and to permit frequent, large-scale, inhabitants screening. Testing is straightforward, fast (outcomes typically accessible inside 15 minutes), and relevant for analysis at level of care.

A narrative review of chimeric antigen receptor-T (CAR-T) cell therapy for lung cancer

However, implementation of Ag RDTs requires an in depth understanding of take a look at efficiency and operational traits in every testing state of affairs and inhabitants being evaluated. Successful implementation of Ag RDTs on a big scale ought to mix testing with technical oversight and with scientific and public well being infrastructure, and would require manufacturing at ranges a lot greater than presently potential.

In this commentary, we offer detailed issues for Ag RDT evaluation and use circumstances to encourage and allow broader manufacturing and deployment.  The S. mansoni an infection charges inferred from POC-CCA and KK have been 40.7% and 9.4% respectively. Good correlations have been noticed between an infection intensities recorded by; i) the reader and visible scoring system on recent (Rho = 0.89) and frozen samples (Rho = 0.97), ii) the reader on recent urine samples and KK (epg) (Rho = 0.44).

Nevertheless, 238 POC-CCA optimistic kids have been unfavourable for KK, and sixteen of them had excessive ranges of CCA. The correlation between outcomes from the reader on recent and frozen samples was good (Rho = 0.85). On frozen samples, CCA was not detected in 55 samples that have been optimistic in recent urine samples.

A Biomimetic Aggregation-Induced Emission Photosensitizer with Antigen-Presenting and Hitchhiking Function for Lipid Droplet Targeted Photodynamic Immunotherapy

Photodynamic therapy (PDT) is a promising various method for efficient cancer remedy that’s related to an antitumor immune response. However, immunosuppression of the tumor microenvironment limits the immune response induced by PDT. Stimulation and proliferation of T cells is a crucial step for producing immune responses and is dependent upon the environment friendly presentation of tumor antigens and co-stimulatory molecules by antigen-presenting cells (APCs).

Here, biomimetic aggregation-induced emission (AIE) photosensitizers with antigen-presenting and hitchhiking skills (DC@AIEdots) are developed by coating dendritic cell (DC) membranes on the nanoaggregates of the AIEgens. Notably, the internal AIE molecules can selectively accumulate in lipid droplets of tumor cells, and the outer cell membrane can facilitate the hitchhiking of DC@AIEdots onto the endogenous T cells and improve the tumor supply effectivity by about 1.6 occasions.

Furthermore, DC@AIEdots can stimulate the in vivo proliferation and activation of T cells and set off the immune system. The potential functions of therapeutic brokers concentrating on lipid droplets for immunotherapy are indicated and a brand new hitchhiking method for drug supply is offered. Lastly, the research presents a photoactive and synthetic antigen-presenting platform for efficient T cell stimulation and cancer photodynamic immunotherapy.

Unusual aggregation property of recombinantly expressed cancer-testis antigens in mammalian cells

Transient expression of human intracellular proteins in human embryonic kidney (HEK) 293 cells is a dependable system for acquiring soluble proteins with biologically lively conformations. Contrary to standard ideas, we discovered that recombinantly expressed intracellular cancer-testis antigens (CTAs) confirmed frequent aggregation in HEK293 cells.

Although experimental subcellular localization of recombinant CTAs displayed correct cytosolic or nuclear localization, some proteins confirmed aggregated particles within the cell. This aggregative property was not noticed in recombinant housekeeping proteins.

RHCE Polyclonal Antibody
ABP60159-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of RHCE from Human. This RHCE antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human RHCE protein at amino acid sequence of 161-210

RHCE Polyclonal Antibody
ABP60159-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of RHCE from Human. This RHCE antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human RHCE protein at amino acid sequence of 161-210

Anti-RHCE antibody
STJ192535 200 µl
EUR 197
Description: Unconjugated Rabbit polyclonal to RHCE

RHCE Polyclonal Antibody
ES11377-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against RHCE from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

RHCE Polyclonal Antibody
ES11377-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against RHCE from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

RHCE Conjugated Antibody
C40210 100ul
EUR 397

HEK-293T Telomerase Over-Expressing Cell Pellet
abx069991-1Pellet 1 Pellet
EUR 398

RHCE Recombinant Protein (Human)
RP042868 100 ug Ask for price

Human RHCE shRNA Plasmid
20-abx954074
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

RHCE ORF Vector (Human) (pORF)
ORF014290 1.0 ug DNA
EUR 354

Chymase reagent
30C-CP1129 5 units
EUR 2185
Description: Purified native Human Chymase reagent

Traut's Reagent
2330-1000
EUR 349

Traut's Reagent
2330-500
EUR 207

MTS Reagent
2808-1000
EUR 990

MTS Reagent
2808-250
EUR 365

MTT Reagent
2809-1G
EUR 180

MTT Reagent
2809-5G
EUR 544

BOP reagent
5-02141 25g Ask for price

BOP reagent
5-02142 100g Ask for price

Bradford reagent
BDE641 100ml
EUR 61.01

Beaucage reagent
HY-100951 10mM/1mL
EUR 126

BOP reagent
A7015-100000 100 g
EUR 200
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.

BOP reagent
A7015-25000 25 g
EUR 113
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.

Bluing Reagent
BRT030 30 ml
EUR 60

Bluing Reagent
BRT125 125 ml
EUR 63

Bluing Reagent
BRT3800 1 Gal.
EUR 184

Bluing Reagent
BRT500 500 ml
EUR 76

Bluing Reagent
BRT999 1000 ml
EUR 88

RHCE sgRNA CRISPR Lentivector set (Human)
K1820001 3 x 1.0 ug
EUR 339

Polyclonal RHCE antibody - N-terminal region
APR00846G 0.05mg
EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RHCE - N-terminal region. This antibody is tested and proven to work in the following applications:

HAMA blocking reagent
85R-1001 1 gram
EUR 1974
Description: HAMA Blocking Reagent for use in immunoassays such as ELISA

HAMA blocking reagent
85R-1001P 1 gram
EUR 2190
Description: HAMA Blocking Reagent for use in immunoassays such as ELISA

HAMA blocking reagent
85R-1003 1 gram
EUR 1974
Description: HAMA Blocking Reagent for use in immunoassays such as Rapid Tests

HAMA blocking reagent
85R-1014 50 mg
EUR 192
Description: HAMA blocking reagent for use in assays specific for clinical false positive samples

HAMA blocking reagent
85R-1025 50 mg
EUR 192
Description: HAMA blocking reagent for use in immunoassays

HAMA blocking reagent
85R-1026 50 mg
EUR 192
Description: HAMA blocking reagent for use in immunoassays

ExFect2000 Transfection Reagent
T202-01 0.5 ml
EUR 227

ExFect2000 Transfection Reagent
T202-02 1 ml
EUR 316

ExFect2000 Transfection Reagent
T202-03 5 ml
EUR 1052

BSA (Reagent Grade)
30-AB79 1 kg
EUR 1552
Description: Reagent Grade Bovine Serum Albumin (99% pure)

BSA (Reagent Grade)
30-AB81 200 grams
EUR 476
Description: Reagent Grade Sulphydryl Blocked BSA (99% pure)

BODIPY-Acetylene Reagent
2594-1
EUR 207

BODIPY-Acetylene Reagent
2594-5
EUR 675

Biotin reagent (HRP)
65C-CE0202 5 mg
EUR 244
Description: HRP conjugated biotin labelling reagent

Bradford Dye Reagent
0209R 100 ml
EUR 131

BCA Reagent, 16ML
C144-16ML 16ML
EUR 163

Dissociation Reagent, 1ML
X017-1ML 1ML
EUR 109

Dissociation Reagent, 25ML
X017-25ML 25ML
EUR 258

Dissociation Reagent, 5ML
X017-5ML 5ML
EUR 122

Dissociation Reagent, 1ML
X058-1ML 1ML
EUR 73

Dissociation Reagent, 5ML
X058-5ML 5ML
EUR 109

Biolipidure-1002-Reagent
Biolipidure-1002-10 10mL
EUR 196
Description: The Biolipidure-1002-Reagent is a synthetic amphoteric polymer that can be substituted for BSA in tubidimetric immunoassays. Biolipidure-1002 is an excellent blocker and also enhances assay sensitivity. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Convoy? Transfection Reagent
1110-1ml
EUR 341

Griess Reagent Kit
30100 1KIT
EUR 149
Description: Minimum order quantity: 1 unit of 1KIT

PhosphoBlocker Blocking Reagent
AKR-103 1L
EUR 328
Description: Most commercially available Western blot blockers, such as dry milk or serum, are sufficient to block unreactive sites on the membrane. However, they are not designed to preserve phosphoprotein antigens during blotting. Our PhosphoBLOCKER Blocking Reagent provides superior blocking by maximizing signal-to-noise ratio. The PhosphoBLOCKER reagent particluarly excels with very low levels of endogenous phopsphoproteins.

PhosphoBlocker Blocking Reagent
AKR-104 4L
EUR 711
Description: Most commercially available Western blot blockers, such as dry milk or serum, are sufficient to block unreactive sites on the membrane. However, they are not designed to preserve phosphoprotein antigens during blotting. Our PhosphoBLOCKER Blocking Reagent provides superior blocking by maximizing signal-to-noise ratio. The PhosphoBLOCKER reagent particluarly excels with very low levels of endogenous phopsphoproteins.

Girard's reagent T
20-abx184099
  • EUR 203.00
  • EUR 314.00
  • 100 g
  • 500 g

FcR blocking Reagent
20-abx290024
  • EUR 377.00
  • EUR 516.00
  • 200 tests
  • 400 tests

Detection Reagent A
abx296004-120ul 120 ul
EUR 321

Mycoplasma Prevention Reagent
20-abx298005
  • EUR 203.00
  • EUR 286.00
  • 1 ml
  • 5 ml

EL Transfection Reagent
20-abx098880
  • EUR 384.00
  • EUR 537.00
  • 0.75 ml
  • 1.5 ml

Mycoplasma Prevention Reagent
20-abx098886
  • EUR 425.00
  • EUR 509.00
  • 1 ml
  • 5 ml

TissueDigest Reagent, 20X
T101 10ml
EUR 210

HighGene transfection reagent
RM09014 1000μl
EUR 270

LP4K Transfection Reagent
LP4K 1.0 ml / vial
EUR 304
Description: Lipid based transfection reagent for large plasmid and multiple plasmid transfection in both adhesive and suspenstion cell types.

n-Heptane Reagent
HC5400 1L
EUR 79

Tri-RNA Reagent
FATRR-001 100ml
EUR 236

Tri-RNA Reagent
FATRR-002 50ml
EUR 176

Tri-RNA Reagent
FATRR-003 450ml
EUR 645

DTT (Cleland's reagent)
DB0058 5g
EUR 84.8

DTNB (Ellman's Reagent)
DB0113 5g
EUR 97.85

Ethyl acetate Reagent
EC4600 1L
EUR 79

Biolipidure-1002-Reagent
Biolipidure-1002-100 100mL
EUR 1223
Description: The Biolipidure-1002-Reagent is a synthetic amphoteric polymer that can be substituted for BSA in tubidimetric immunoassays. Biolipidure-1002 is an excellent blocker and also enhances assay sensitivity. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-103-Reagent
Biolipidure-103-10 10mL
EUR 196
Description: The Biolipidure-103-Reagent is a synthetic amphoteric polymer that can be substituted for BSA. It has been shown to enhance signals in rapid tests, western blots, and other similar immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-103-Reagent
Biolipidure-103-100 100mL
EUR 1223
Description: The Biolipidure-103-Reagent is a synthetic amphoteric polymer that can be substituted for BSA. It has been shown to enhance signals in rapid tests, western blots, and other similar immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1201-Reagent
Biolipidure-1201-10 10mL
EUR 196
Description: The Biolipidure-1201 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1201-Reagent
Biolipidure-1201-100 100mL
EUR 1223
Description: The Biolipidure-1201 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1301-Reagent
Biolipidure-1301-10 10mL
EUR 196
Description: The Biolipidure-1301 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1301-Reagent
Biolipidure-1301-100 100mL
EUR 1223
Description: The Biolipidure-1301 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-203-Reagent
Biolipidure-203-10 10mL
EUR 196
Description: The Biolipidure-203 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-203 has been shown to enhance signal strength by improving signal-to-noise in ELISAs, EIAs, and related immunoassays. It also functions as an effective blocker and stabilizer in these assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-203-Reagent
Biolipidure-203-100 100mL
EUR 1223
Description: The Biolipidure-203 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-203 has been shown to enhance signal strength by improving signal-to-noise in ELISAs, EIAs, and related immunoassays. It also functions as an effective blocker and stabilizer in these assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-206-Reagent
Biolipidure-206-10 10mL
EUR 196
Description: The Biolipidure-206 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-206 enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-206-Reagent
Biolipidure-206-100 100mL
EUR 1223
Description: The Biolipidure-206 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-206 enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-405-Reagent
Biolipidure-405-10 10mL
EUR 196
Description: The Biolipidure-405 Reagent is a synthetic anionic polymer that can be used to enhance immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-405-Reagent
Biolipidure-405-100 100mL
EUR 1223
Description: The Biolipidure-405 Reagent is a synthetic anionic polymer that can be used to enhance immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-502-Reagent
Biolipidure-502-10 10mL
EUR 196
Description: The Biolipidure-502 Reagent is a synthetic cationic polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-502-Reagent
Biolipidure-502-100 100mL
EUR 1223
Description: The Biolipidure-502 Reagent is a synthetic cationic polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-702-Reagent
Biolipidure-702-10 10mL
EUR 196
Description: The Biolipidure-702 Reagent is a synthetic amphoteric polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-702-Reagent
Biolipidure-702-100 100mL
EUR 1223
Description: The Biolipidure-702 Reagent is a synthetic amphoteric polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-802-Reagent
Biolipidure-802-10 10mL
EUR 196
Description: The Biolipidure-802 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-802 generally enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, Rapid-test, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-802-Reagent
Biolipidure-802-100 100mL
EUR 1223
Description: The Biolipidure-802 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-802 generally enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, Rapid-test, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Alcohol, Reagent (70%)
EAS500 500 ml
EUR 79

Alcohol, Reagent (70%)
EAS999 1000 ml
EUR 101

PureFection Transfection Reagent
LV750A-1 1 ml
EUR 359

Arabidopsis Thaliana Lysate
30R-AA023 150 ug
EUR 156
Description: Arabidopsis Thaliana Plant Lysate

CMV Cell Lysate
35-1867 1 mg
EUR 1835
Description: CMV enriched cell lysate

HSV1 Cell Lysate
35-1872 1 ml
EUR 394
Description: HSV1 enriched cell lysate

HSV2 Cell Lysate
35-1873 1 ml
EUR 394
Description: HSV2 enriched cell lysate

JM109-lysate Antibody
abx234439-100ug 100 ug
EUR 551

DH5a-lysate Antibody
abx232362-100ug 100 ug
EUR 551

BL21-lysate Antibody
abx230905-100ug 100 ug
EUR 551

Green Algae Lysate
PABL-1306 50 ug
EUR 164

RHCE 3'UTR Luciferase Stable Cell Line
TU019870 1.0 ml
EUR 1394

RHCE 3'UTR GFP Stable Cell Line
TU069870 1.0 ml
EUR 1394

RHCE Protein Vector (Human) (pPB-C-His)
PV057157 500 ng
EUR 481

RHCE Protein Vector (Human) (pPB-N-His)
PV057158 500 ng
EUR 481

RHCE Protein Vector (Human) (pPM-C-HA)
PV057159 500 ng
EUR 481

RHCE Protein Vector (Human) (pPM-C-His)
PV057160 500 ng
EUR 481

RHCE sgRNA CRISPR Lentivector (Human) (Target 1)
K1820002 1.0 ug DNA
EUR 154

RHCE sgRNA CRISPR Lentivector (Human) (Target 2)
K1820003 1.0 ug DNA
EUR 154

RHCE sgRNA CRISPR Lentivector (Human) (Target 3)
K1820004 1.0 ug DNA
EUR 154

Rh Blood Group CcEe Antigens (RHCE) Antibody
20-abx339688
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Rh Blood Group CcEe Antigens (RHCE) Antibody
abx413595-02mg 0.2 mg
EUR 565

Rh Blood Group CcEe Antigens (RHCE) Antibody
abx413596-25ug 25 ug
EUR 272

Rh Blood Group CcEe Antigens (RHCE) Antibody
20-abx211379
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Chicken IgY precipitation reagent
85R-1010 4 ml
EUR 554
Description: Chicken IgY precipitation reagent for use in immunoassays

Mouse IgG Blocking Reagent
30R-AH071 20 mg
EUR 258
Description: Mouse IgG (H + L) Blocking Reagent

Biotin reagent (Alk Phos)
65C-CE0201 1 mg
EUR 211
Description: Alkaline Phosphatase conjugated biotin labelling reagent

Biotin reagent (Glucose Oxidase)
65C-CE0203 5 mg
EUR 232
Description: Glucose Oxidase conjugated biotin labelling reagent

Annexin V-Cy5 Reagent
1013-1000
EUR 1132

Annexin V-Cy5 Reagent
1013-200
EUR 403

Annexin V-PE Reagent
1014-1000
EUR 1132

Annexin V-PE Reagent
1014-200
EUR 403

Annexin V-FITC Reagent
1001-1000
EUR 1246

Annexin V-FITC Reagent
1001-200
EUR 441

Annexin V-Cy3 Reagent
1002-1000
EUR 1132

Annexin V-Cy3 Reagent
1002-200
EUR 403

Annexin V-Biotin Reagent
1003-100
EUR 370

Annexin V-Biotin Reagent
1003-1000
EUR 2388

Annexin V-EGFP Reagent
1004-1000
EUR 1132

Annexin V-EGFP Reagent
1004-200
EUR 403

Cytotoxicity Control Reagent (Saponin)
CTTX-050 (50mg)
EUR 135
Description: To be used as a cytotoxic control agent in the CellQuanti-BlueTM and CellQuanti-MTTTM Cell Viability Assay Kits. IC50 = 0.002 wt%. Kit size: (50mg) tests. Shelf life: 12 months. Shipping: ambient temp; storage: 4°C.

MESG *Phosphate assay reagent*
21600 5 mg
EUR 115

Creatinine Color Reagent, 28ML
C004-28ML 28ML
EUR 268

GST Detection Reagent, 1EA
C035-1EA 1EA
EUR 237

Hemoglobin Detection Reagent, 20ML
C038-20ML 20ML
EUR 258

Hydrogen Peroxide Reagent, 5ML
C115-5ML 5ML
EUR 123

Fluorescent Detection Reagent, 5ML
C116-5ML 5ML
EUR 268

Hydrogen Peroxide Reagent, 5ML
C132-5ML 5 ML
EUR 123

FRAP Reagent A, 1.4ML
C148-1.4ML 1.4ML
EUR 178

FRAP Reagent B, 1.4ML
C149-1.4ML 1.4ML
EUR 178

Detection Reagent Concentrate, 1ML
X041-1ML 1ML
EUR 143

Color Reagent A, 5ML
X092-5ML 5ML
EUR 109

Color Reagent B, 5ML
X093-5ML 5ML
EUR 109

Color Reagent A, 15ML
X094-15ML 15ML
EUR 122

Color Reagent A, 38ML
X094-38ML 38ML
EUR 153

Color Reagent B, 15ML
X095-15ML 15ML
EUR 122

Color Reagent B, 38ML
X095-38ML 38ML
EUR 153

Block-Free ELISA Reagent
M4102-250
EUR 452

Block-Free ELISA Reagent
M4102-50
EUR 147

GeneGlide? DNA Transfection Reagent
M1080-1000
EUR 530

GeneGlide? DNA Transfection Reagent
M1080-300
EUR 269

GeneGlide? DNA Transfection Reagent
M1080-500
EUR 361

GeneGlide? siRNA Transfection Reagent
M1081-1000
EUR 445

GeneGlide? siRNA Transfection Reagent
M1081-300
EUR 265

GeneGlide? siRNA Transfection Reagent
M1081-500
EUR 304

Carrez Clarification Reagent Kit
K809-100
EUR 245

Bacteria RNA Plus Reagent
R402-01 20 ml
EUR 130

RNA-easy Isolation Reagent
R701-01 100 ml
EUR 168

RNA-easy Isolation Reagent
R701-02 200 ml
EUR 212

QuantiFluo ALP Detection Reagent
QFALP-6mL 600
EUR 156
Description: A stable 4-methylumbelliferyl phosphate (MUP) liquid substrate reagent formulated for detecting alkaline phosphatase ALP, e.g. in ELISA. This single reagent produces a highly fluorescent product (360/450 nm) when dephosphorylated by ALP. The fluorescent p

QuantiFluo HRP Detection Reagent
QFHRP-25mL 500
EUR 243
Description: A stable 10-Acetyl-3,7-dihydroxyphenoxazine (also called Ampliflu Red) liquid substrate reagent formulated for detecting horseradish peroxidase HRP activity, e.g. in ELISA. This reagent produces a highly fluorescent product (530/590nm) upon reaction with

DIRECTPCR LYSIS REAGENT (TAIL)
101-T 50 ml
EUR 141
Description: Up to 250 tails (50ml)

DIRECTPCR LYSIS REAGENT (TAIL)
102-T 100ml
EUR 207
Description: Up to 500 tails (50ml)

REAGENT BOTTLE, 1L, PP
1500P-1L 10/pk
EUR 100
Description: Reusable Plastics; Resusable Bottles

One Step-RNA Reagent
BS409A 25ml
EUR 69.03

One Step-RNA Reagent
BS410A 100ml
EUR 110.9

Universal Protein Precipitating Reagent
BSP012 100preps
EUR 81.32

Folin & Ciocalteu’s phenol reagent
abx082175-50ml 50 ml
EUR 189

DIRECTPCR LYSIS REAGENT (CELL)
301-C 50 ml
EUR 141
Description: For use with cultured cells

DIRECTPCR LYSIS REAGENT (CELL)
302-C 100 ml
EUR 207
Description: For use with cultured cells

DIRECTPCR LYSIS REAGENT (EAR)
401-E 25 ml
EUR 141
Description: For use with ear pieces

DIRECTPCR LYSIS REAGENT (EAR)
402-E 50 ml
EUR 207
Description: For use with ear pieces

iMFectin DNA Transfection Reagent
I7100-100 100ul
EUR 147

iMFectin DNA Transfection Reagent
I7100-101 1ml
EUR 442

iMFectin DNA Transfection Reagent
I7100-105 5x1ml
EUR 1873

iMFectin DNA Transfection Reagent
I7100-120 20ml
EUR 6787

Transfection Reagent (1 mL)
P901 - Ask for price

Transfection Reagent (0.1 mL)
P901S - Ask for price

DMPO (Spin trapping reagent)
SIH-324-125MG 125 mg
EUR 213
Description: The substance DMPO is a spin trapping reagent. It is synthetically produced and has a purity of >98%. The pure substance is liquid which is soluble to 100 mM in ethanol and to 100 mM in DMSO.

DMPO (Spin trapping reagent)
SIH-324-25MG 25 mg
EUR 98
Description: The substance DMPO is a spin trapping reagent. It is synthetically produced and has a purity of >98%. The pure substance is liquid which is soluble to 100 mM in ethanol and to 100 mM in DMSO.

100 BlotBot Reagent Reservoirs
RRVR-100 100pack
EUR 177
Description: BlotBot reagent reservoirs will allow dispensing of unique reagents during processing. Pack of 100.

500 BlotBot Reagent Reservoirs
RRVR-500 500pack
EUR 534
Description: BlotBot reagent reservoirs will allow dispensing of unique reagents tray during processing. Pack of 500.

Lentifectin (TM) Transfection Reagent
DNAF003 1ml
EUR 278.81

Drying Reagent, Silica Gel
DSG110 1Kg
EUR 76.1

Biotin-XX Tyramide Reagent
A8012-10 10 mg
EUR 166
Description: Biotin-LC-LC-tyramide is used for tyramide signal amplification (TSA) which is a powerful, patented technology that significantly enhances both chromogenic and fluorescent signals. TSA is easily integrated into standard nonradioactive in situ hybridization (ISH) or IHC protocols

Biotin-XX Tyramide Reagent
A8012-100 100 mg
EUR 862
Description: Biotin-LC-LC-tyramide is used for tyramide signal amplification (TSA) which is a powerful, patented technology that significantly enhances both chromogenic and fluorescent signals. TSA is easily integrated into standard nonradioactive in situ hybridization (ISH) or IHC protocols

Biotin-XX Tyramide Reagent
A8012-1000 1 g
EUR 2602
Description: Biotin-LC-LC-tyramide is used for tyramide signal amplification (TSA) which is a powerful, patented technology that significantly enhances both chromogenic and fluorescent signals. TSA is easily integrated into standard nonradioactive in situ hybridization (ISH) or IHC protocols

No important correlation was discovered between the aggregative and biophysical properties, reminiscent of hydrophobicity, contents of intrinsically disordered areas, and expression ranges, of CTAs.

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