DNA-protein and protein-protein interactions

Insights into gene regulation: From regulatory genomic components to DNA-protein and protein-protein interactions Transcription is orchestrated by non-coding regulatory components embedded in chromatin, which exist inside the bigger context of chromosome topology. Here, we evaluate latest insights into the capabilities of non-coding regulatory components and their protein interactors throughout transcription management. An image emerges through which … Read more

Removal of Endotoxin from rAAV Samples Using a Simple Detergent-Based Protocol.

Removal of Endotoxin from rAAV Samples Using a Simple Detergent-Based Protocol.

Endotoxin is the commonest contaminant present in protein samples. Even a small quantity of endotoxin can induce sturdy allergic response and loss of life of a host organism. Endotoxin can also be typically detected in recombinant adeno-associated virus (rAAV) shares ready in analysis laboratories utilizing off-the-shelf reagents; purifying rAAV shares from endotoxin utilizing business reagents generally … Read more