DNA-protein and protein-protein interactions

January 3, 2021 0 Comments

Insights into gene regulation: From regulatory genomic components to DNA-protein and protein-protein interactions Transcription is orchestrated by non-coding regulatory components embedded in chromatin, which exist inside the bigger context of chromosome topology. Here, we evaluate latest insights into the capabilities of non-coding regulatory components and their protein interactors throughout transcription management. An image emerges through which …

Low pH Exposure During Immunoglobulin G Purification Methods Results in Aggregates That Avidly Bind Fcγ Receptors: Implications for Measuring Fc Dependent Antibody Functions.

Low pH Exposure During Immunoglobulin G Purification Methods Results in Aggregates That Avidly Bind Fcγ Receptors: Implications for Measuring Fc Dependent Antibody Functions.
May 10, 2020 0 Comments

Evaluating the biophysical and practical nature of IgG is essential to defining correlates of safety in infectious illness, and autoimmunity analysis cohorts, in addition to vaccine efficacy trials. These research typically require small portions of IgG to be purified from plasma for downstream evaluation with excessive throughput immunoaffinity codecs which elute IgG at low-pH, resembling …